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Recombinant Human FGFR2 Protein, His-tagged

Cat.No. : FGFR2-778H
Product Overview : Recombinant human FGFR2-alpha(IIIb) (NP_075259.4) (Met1-Glu378) was expressed with a polyhistidine tag at the C-terminus.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Arg 22
Form : Lyophilized from sterile PBS, pH 7.4, 5% ~ 8% trehalose and mannitol.
Molecular Mass : The recombinant human FGFR2-alpha(IIIb) consists 368 amino acids and predicts a molecular mass of 41.1 kDa.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ]
Official Symbol : FGFR2
Synonyms : FGFR2; fibroblast growth factor receptor 2; bacteria expressed kinase , BEK, CFD1, craniofacial dysostosis 1 , Jackson Weiss syndrome , JWS, keratinocyte growth factor receptor , KGFR; CD332; CEK3; Crouzon syndrome; ECT1; K SAM; Pfeiffer syndrome; TK14; TK25; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14; BEK; JWS; CFD1; KGFR; BFR-1; K-SAM; FLJ98662;
Gene ID : 2263
mRNA Refseq : NM_000141
Protein Refseq : NP_000132
MIM : 176943
UniProt ID : P21802
Chromosome Location : 10q25.3-q26
Pathway : Angiogenesis, organism-specific biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is FGFR2 linked to developmental disorders? 01/01/2022

Mutations in FGFR2 are associated with various developmental disorders, impacting the development of the skull, limbs, and other structures.

Can FGFR2 be targeted for personalized cancer therapy? 04/19/2021

Yes, targeting FGFR2 mutations allows for more personalized and precise therapeutic approaches in cancer treatment.

Are there clinical trials involving FGFR2 inhibitors? 01/24/2020

Yes, numerous clinical trials are underway to evaluate the efficacy of FGFR2 inhibitors in treating various cancers and developmental disorders.

How does FGFR2 impact wound healing? 02/28/2019

FGFR2 is involved in the regulation of cell migration and tissue repair, contributing to the process of wound healing.

Are there any side effects associated with FGFR2 inhibitors? 08/28/2018

Common side effects of FGFR2 inhibitors include fatigue, nausea, and hypertension, which are being studied for better management.

Customer Reviews (3)

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Reviews
08/24/2017

    The FGFR2 protein is an outstanding product that possesses exceptional quality, making it an ideal choice for my experimental needs.

    03/05/2017

      What sets FGFR2 apart is the manufacturer's unparalleled technical support.

      09/13/2016

        The versatility of the FGFR2 protein makes it a valuable asset in my research.

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