Active Recombinant Human FGFR3 protein, Fc-tagged
Cat.No. : | FGFR3-779H |
Product Overview : | Recombinant Human FGFR3 protein(Glu 23 - Gly 377), fused with Fc tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Human FGF basic, premium grade at 5 μg/mL (100 μL/well) can bind Human FGF R3 (IIIb), Fc Tag with a linear range of 2-39 ng/mL.Immobilized Biotinylated Human FGF basic, Avitag,His Tag at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate can bind Human FGF R3 (IIIb), Fc Tag with a linear range of 1-39 ng/mL. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminus.The protein has a calculated MW of 65.0 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Glu23-Gly377 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please protect from light and avoid repeated freeze-thaw cycles.This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ] |
Official Symbol : | FGFR3 |
Synonyms : | FGFR3; fibroblast growth factor receptor 3; ACH, achondroplasia, thanatophoric dwarfism; CD333; CEK2; JTK4; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; ACH; HSFGFR3EX; |
Gene ID : | 2261 |
mRNA Refseq : | NM_000142 |
Protein Refseq : | NP_000133 |
MIM : | 134934 |
UniProt ID : | P22607 |
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◆ Lysates | ||
FGFR3-001CCL | Recombinant Cynomolgus FGFR3 cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFGFR3 testing helps identify specific genetic mutations, allowing for personalized treatment plans tailored to an individual's genetic profile.
FGFR3 testing is becoming more common, especially in cases where specific cancers associated with FGFR3 mutations are suspected.
Yes, FGFR3 status can serve as a prognostic marker, influencing the prediction of disease progression and patient outcomes.
Yes, FGFR3-targeted therapies are being developed for cancer treatment, particularly for patients with FGFR3 mutations.
FGFR3-targeted therapies may involve small molecule inhibitors or monoclonal antibodies that specifically block the activity of mutated FGFR3.
Customer Reviews (3)
Write a reviewResearchers who have utilized FGFR3 protein praise its exceptional performance and reliability in their experiments.
Its high sensitivity enables the identification of low abundance targets, making it highly valuable in immunological research.
Its stability and compatibility with electron microscopy techniques make it an ideal candidate for studying protein structures at high resolution.
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