Recombinant Human FGFR3 Protein, His-tagged

Cat.No.: FGFR3-752H
Product Overview: Recombinant human FGFR3 (NP_000133.1) (Met1-Gly375) was expressed with a polyhistidine tag at the C-terminus.
Source: HEK293
Species: Human
Tag: His
Predicted N Terminal: Glu 23
Form: Lyophilized from sterile PBS, pH 7.4, 5% ~ 8% trehalose and mannitol.
Molecular Mass: The recombinant human FGFR3 consists 364 amino acids and predicts a molecular mass of 39.6 kDa.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: >95 % as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ]
Official Symbol: FGFR3
Synonyms: FGFR3; fibroblast growth factor receptor 3; ACH, achondroplasia, thanatophoric dwarfism; CD333; CEK2; JTK4; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; ACH; HSFGFR3EX;
Gene ID: 2261
mRNA Refseq: NM_000142
Protein Refseq: NP_000133
MIM: 134934
UniProt ID: P22607
Chromosome Location: 4p16.3
Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FGFR ligand binding and activation, organism-specific biosystem;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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