Recombinant Human FOXP3, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
>80% as determined by SDS-PAGE and Coomassie blue staining
>50 ug/mL as determined by microplate BCA method