Recombinant Human FTL protein, MYC/DDK-tagged
Cat.No. : | FTL-65H |
Product Overview : | Recombinant Human FTL fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
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Description : | This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 19.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | FTL ferritin, light polypeptide [ Homo sapiens ] |
Official Symbol : | FTL |
Synonyms : | FTL; ferritin, light polypeptide; ferritin light chain; ferritin L subunit; ferritin L chain; ferritin light polypeptide like 3; L apoferritin; MGC71996; ferritin L-chain; ferritin light polypeptide-like 3; NBIA3; |
Gene ID : | 2512 |
mRNA Refseq : | NM_000146 |
Protein Refseq : | NP_000137 |
MIM : | 134790 |
UniProt ID : | P02792 |
Chromosome Location : | 19q13.33 |
Pathway : | Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; |
Function : | ferric iron binding; ferroxidase activity; identical protein binding; iron ion binding; oxidoreductase activity; |
Products Types
◆ Recombinant Protein | ||
FTL-6939H | Recombinant Human FTL protein(Met1-Asp175), His-tagged | +Inquiry |
FTL-2059R | Recombinant Rat FTL Protein, His (Fc)-Avi-tagged | +Inquiry |
FTL-400H | Recombinant Human FTL Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
FTL-4533H | Recombinant Human FTL Protein, GST-tagged | +Inquiry |
FTL-1579R | Recombinant Rhesus Macaque FTL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
FTL-26944TH | Native Human FTL | +Inquiry |
FTL-673H | Native Human Ferritin, Light Polypeptide | +Inquiry |
◆ Lysates | ||
FTL-6126HCL | Recombinant Human FTL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionCurrent studies have shown that abnormal iron metabolism may be related to Alzheimer's disease, and FTL protein is one of the key proteins in iron metabolism. Therefore, FTL protein may be involved in the occurrence and progression of Alzheimer's disease. However, further research is needed to confirm the specific relationship.
Abnormal levels of FTL protein can lead to a variety of health problems such as abnormal iron metabolism, anemia, neuropathy, heart disease, immune system abnormalities, and diabetes.
Research is currently underway to develop new therapeutics using FTL protein as a target, such as improving symptoms of abnormal iron metabolism and related diseases by modulating the expression and function of FTL protein. However, further research and clinical trial validation are needed for specific applications.
Prevention of FTL protein-related diseases is mainly by maintaining a healthy lifestyle, such as a balanced diet, moderate exercise, and avoiding excessive intake of iron-containing drugs. In addition, regular check-ups and related examinations can also help to detect potential problems early.
Current studies have shown that multiple sclerosis may be related to abnormal iron metabolism, and FTL protein is one of the key proteins in iron metabolism, so it may be related to the occurrence and progression of multiple sclerosis. However, further research is needed to confirm the specific relationship.
Lifestyle changes, such as healthy diet and moderate exercise, can affect the function and expression level of FTL protein. These changes can promote normal iron metabolism, which can help maintain good health.
Customer Reviews (3)
Write a reviewFTL has very good antigenicity and can induce target immune response.
FTL has high sensitivity and strong specificity.
The catalytic efficiency is high and the time consuming is short, which greatly saves the time of the experimental members.
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