Recombinant Human GPNMB protein, His-tagged
Cat.No. : | GPNMB-3783H |
Product Overview : | Recombinant Human GPNMB protein (Ala22-Pro486), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 52.9 kDa. The protein migrates as 85-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 465 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | GPNMB |
Official Symbol : | GPNMB |
Synonyms : | GPNMB; glycoprotein (transmembrane) nmb; transmembrane glycoprotein NMB; glycoprotein NMB; glycoprotein nmb like protein; HGFIN; NMB; osteoactivin; transmembrane glycoprotein; glycoprotein nmb-like protein; transmembrane glycoprotein HGFIN |
Gene ID : | 10457 |
mRNA Refseq : | NM_001005340 |
Protein Refseq : | NP_001005340 |
MIM : | 604368 |
UniProt ID : | Q14956 |
Products Types
◆ Recombinant Protein | ||
Gpnmb-3290M | Recombinant Mouse Gpnmb Protein, Myc/DDK-tagged | +Inquiry |
GPNMB-2238H | Recombinant Human GPNMB Protein, MYC/DDK-tagged | +Inquiry |
GPNMB-5162H | Recombinant Human GPNMB Protein, GST-tagged | +Inquiry |
GPNMB-3782H | Recombinant Human GPNMB protein(Met1-Pro474), His-tagged | +Inquiry |
GPNMB-82H | Recombinant Human GPNMB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GPNMB-1423MCL | Recombinant Mouse GPNMB cell lysate | +Inquiry |
GPNMB-1886HCL | Recombinant Human GPNMB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket