Recombinant Human GZMB protein, GST-tagged
Cat.No. : | GZMB-35H |
Product Overview : | Recombinant Human GZMB(1 a.a. - 247 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 54.1 kDa |
AA Sequence : | MQPILLLLAFLLLPRADAGEIIGGH EAKPHSRPYMAYLMIWDQKSLKRCG GFLIQDDFVLTAAHCWGSSINVTLG AHNIKEQEPTQQFIPVKRPIPHPAY NPKNFSNDIMLLQLERKAKRTRAVQ PLRLPSNKAQVKPGQTCSVAGWGQT APLGKHSHTLQEVKMTVQEDRKCES DLRHYYDSTIELCVGDPEIKKTSFK GDSGGPLVCNKVAQGIVSYGRNNGM PPRACTKVSSFVHWIKKTMKRH |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) [ Homo sapiens ] |
Official Symbol : | GZMB |
Synonyms : | GZMB; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); CSPB, CTLA1; granzyme B; cathepsin G like 1; CCPI; CGL 1; CGL1; CSP B; CTSGL1; cytotoxic serine protease B; fragmentin 2; HLP; SECT; T cell serine protease 1 3E; C11; CTLA-1; fragmentin-2; cathepsin G-like 1; human lymphocyte protein; T-cell serine protease 1-3E; cytotoxic T-lymphocyte proteinase 2; CSPB; CGL-1; CSP-B; CTLA1; |
Gene ID : | 3002 |
mRNA Refseq : | NM_004131 |
Protein Refseq : | NP_004122 |
MIM : | 123910 |
UniProt ID : | P10144 |
Chromosome Location : | 14q11.2 |
Pathway : | Activation, myristolyation of BID and translocation to mitochondria, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; |
Function : | catalytic activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type endopeptidase activity; serine-type peptidase activity; |
Products Types
◆ Recombinant Protein | ||
GZMB-2425R | Recombinant Rat GZMB Protein, His (Fc)-Avi-tagged | +Inquiry |
Gzmb-273G | Active Recombinant Mouse Gzmb Protein (227 aa) | +Inquiry |
Gzmb-2516M | Recombinant Mouse Gzmb Protein | +Inquiry |
Gzmb-070M | Active Recombinant Mouse Gzmb Protein | +Inquiry |
Gzmb-4520M | Recombinant Mouse Gzmb Protein | +Inquiry |
◆ Lysates | ||
GZMB-2944HCL | Recombinant Human GZMB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0404 | GZMB Assay/Inhibitor Screening Fluorometric Kit | +Inquiry |
Kit-0403 | GZMB Activity Fluorometric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket