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Home > Products > Recombinant Proteins > Recombinant Human HLA-A protein, MYC/DDK-tagged

Recombinant Human HLA-A protein, MYC/DDK-tagged

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"HLA-A" Related Products.
By Species
Human(3)
By Source
By Tag
MYC/DDK(1)
Cat.No.:
HLA-A-938H
Product Overview:
Recombinant Human HLA-A fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description:
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.
Source:
HEK293
Species:
Human
Tag:
MYC/DDK
Form:
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass:
38.5 kDa
Purity:
> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:
>50 ug/mL as determined by microplate BCA method


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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