Recombinant Human HLA-B(aa 26-309) fused with His/T7 tag was expressed in E. coli.
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons.
Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
Store at +4 centigrade for up to 1 month, or aliquot and store at -80 centigrade for up to 12 months. Avoid repeat freeze-thaw cycles.
Reconstitute in sterile PBS, pH 7.2-7.4.