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Active Recombinant Human HTRA4 protein, His-tagged

Cat.No. : HTRA4-790H
Product Overview : Recombinant human HTRA4 protein fragment (138 to 476 aa) was expressed in E. coli with C-terminus his tag.
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  • Gene Information
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Description : This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
Source : E. coli
Species : Human
Tag : His
Form : 0.64% Tris HCl, 15% Glycerol, 0.704% Sodium chloride, 0.816% Imidazole, pH 7.5.
Bio-activity : Proteolytic activity of this product was documented by digestion of ß- casein. 0.5 mg ß-casein/ml are completely digested by 10 µg/ml HTRA4 within 24 hours at 37 centigrade.
Molecular Mass : 38 kDa
AA Sequence : MRLGKVPAVPVQWGNCGDTGTRSAG PLRRNYNFIAAVVEKVAPSVVHVQL WGRLLHGSRLVPVYSGSGFIVSEDG LIITNAHVVRNQQWIEVVLQNGARY EAVVKDIDLKLDLAVIKIESNAELP VLMLGRSSDLRAGEFVVALGSPFSL QNTATAGIVSTKQRGGKELGMKDSD MDYVQIDATINYGNSGGPLVNLDGD VIGVNSLRVTDGISFAIPSDRVRQF LAEYHEHQMKGKAFSNKKYLGLQML SLTVPLSEELKMHYPDFPDVSSGVY VCKVVEGTAAQSSGLRDHDVIVNIN GKPITTTTDVVKALDSDSLSMAVLR GKDNLLLTVIPETINHHHHHH
Purity : >90% by SDS-PAGE
Storage : Store at -80 centigrade. Avoid freeze-thaw cycles.
Concentration : 0.1 mg/mL
Gene Name : HtrA serine peptidase 4 [ Homo sapiens ]
Official Symbol : HTRA4
Synonyms : HTRA4; HtrA serine peptidase 4; probable serine protease HTRA4; FLJ90724
Gene ID : 203100
mRNA Refseq : NM_153692
Protein Refseq : NP_710159
MIM : 610700
UniProt ID : P83105

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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