Active Recombinant Human IGHG1 Protein
Cat.No. : | IGHG1-245H |
Product Overview : | Recombinant human IgG1 Fc region (AAC82527.1) (Glu 99-Lys 330) (one aa mutation,103 Cys/Ser) was expressed. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Predicted N Terminal : | Glu 99 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Bio-activity : | 1. Measured by its ability to bind human CD16a-His in a functional ELISA.2. Measured by its ability to bind human CD16a-AVI-His in a functional ELISA.3.Measured by its ability to bind human CD16a-His in a functional ELISA. |
Molecular Mass : | The recombinant human IgG1 Fc consists of 232 amino acids and has a predicted molecular mass of 26 kDa. As a result of glycosylation, the apparent molecular mass of rhFc is approximately 32 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) [ Homo sapiens ] |
Official Symbol : | IGHG1 |
Synonyms : | IGHG1 |
Gene ID : | 3500 |
mRNA Refseq : | |
Protein Refseq : | |
MIM : | |
UniProt ID : | |
Chromosome Location : | 14q32.33 |
Pathway : | Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Fcgamma receptor (FCGR) dependent phagocytosis, organism-specific biosystem |
Products Types
◆ Recombinant Protein | ||
IGHG1-575H | Recombinant Human IGHG1 Protein (1-330 aa), His-SUMO-tagged | +Inquiry |
IGHG1-1636H | Recombinant Human IGHG1 Protein, Fc-tagged | +Inquiry |
IGHG1-91H | Recombinant Human IGHG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGHG1-4763H | Recombinant Human IGHG1 protein | +Inquiry |
IGHG1-372H | Active Recombinant Human IGHG1 protein, His & Avi-tagged, Biotinylated | +Inquiry |
◆ Native Protein | ||
IGHG1-617H | Native Human Immunoglobulin Heavy Constant Gamma 1 (G1m marker) | +Inquiry |
ighg1-160M | Native Mouse Immunoglobulin G1 | +Inquiry |
◆ Lysates | ||
IGHG1-841HCL | Recombinant Human IGHG1 cell lysate | +Inquiry |
IgG1-2886MCL | Recombinant Mouse IgG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionYes, IGHG1 protein regulates the activity and function of immune cells by interacting with their receptors.
IGHG1 protein is expressed at abnormal levels in some immune diseases and can be detected as one of the markers of diseases, such as rheumatoid arthritis.
IGHG1 protein is involved in humoral immunity, protecting the body from infection by interacting with pathogens, neutralizing toxins, and assisting in the phagocytosis of immune cells.
Yes, there may be a correlation between IGHG1 protein and response to immunotherapy, and researchers are exploring it as a predictor of immunotherapy.
Yes, the IGHG1 protein is an important component involved in antibody-dependent cytotoxicity (ADCC) and enhances cytotoxicity by interacting with effector cells.
Yes, some studies have found that the expression level of IGHG1 protein is related to the severity of immune diseases, which may be one of the indicators to evaluate disease progression and prognosis.
Customer Reviews (3)
Write a reviewGood stability, suitable for long-term storage.
It can induce specific immune response accurately and stably, which is of great application value.
Fluorescent labeling works very well, it helps with imaging studies, it works very well.
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