Recombinant Human IGHG3 protein

• Cat.No.: IGHG3-20H
• Product Overview: Recombinant Human IGHG3 (Glu 99 - Lys 377) was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Predicted N Terminal: Glu 99
• Form: Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
• Molecular Mass: Has a calculated MW of 31.2 kDa. The reducing (R) protein migrates as 40-50 kDa in SDS-PAGE due to glycosylation.
• Protein length: Glu 99 - Lys 377
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade).

Gene Information

• Gene Name: IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) [ Homo sapiens ]
• Official Symbol: IGHG3
• Synonyms: IgG3; C gamma 3; constant region of heavy chain of IgG3; immunoglobulin gamma 3 (Gm marker); immunoglobulin heavy constant gamma 3 (Gm marker); secrete-type Ig gamma heavy-chain
• Gene ID: 3502
• Chromosome Location: 14q32.33
• Pathway: Classical antibody-mediated complement activation, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: antigen binding; immunoglobulin receptor binding