Recombinant Human IL17A/IL17F protein

• Cat.No.: IL17AF-12H
• Product Overview: A DNA sequence encoding the human IL17A ( NP_002181.1) (Met 1 - Ala 155) was expressed,constructed the plasmid 1;the human IL17F (NP_443104.1) (Met 1 - Gln 163) was expressed, constructed the plasmid 2. The two plasmids were co-expressed and the heterodimer was purified.

Specification

• Source: E. coli
• Species: Human
• Predicted N Terminal: Gly24 & Arg31
• Form: Lyophilized from sterile PBS, pH 7.4.
• Molecular Mass: The recombinant heterodimer of human IL17A & IL17F comprises 265 (132+133) amino acids and has a calculated molecular mass of 30 (15.1+14.9) kDa.
• Purity: > 95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade
• Storage: Store it under sterile conditions at -20 centigradeto -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL17F interleukin 17F [ Homo sapiens ]
• Official Symbol: IL17F
• Synonyms: IL17F; interleukin 17F; interleukin-17F; IL 17F; ML 1; ML1; IL-24; cytokine ML-1; mutant IL-17F; interleukin-24; ML-1; CANDF6; IL-17F
• Gene ID: 112744
• mRNA Refseq: NM_052872
• Protein Refseq: NP_443104
• MIM: 606496
• UniProt ID: Q96PD4
• Chromosome Location: 6p12
• Pathway: IL23-mediated signaling events, organism-specific biosystem
• Function: cytokine activity; cytokine binding; protein homodimerization activity