Recombinant Human IL17RB Protein, FLAG-tagged
Cat.No. : | IL17RB-484H |
Product Overview : | Recombinant extracellular domain (Arg 18-Gly 289) of human IL17RB (NP_061195.2) was fused with a signal peptide at the N-terminus and a flag tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | Baculovirus-Insect Cells |
Species : | Human |
Tag : | FLAG |
Predicted N Terminal : | Arg 18 |
Form : | Lyophilized from sterile 100mM Glycine, 10mM NaCl, pH 6.0, 5%~8% trehalose and mannitol. |
Molecular Mass : | The secreted recombinant human IL17RB comprises 280 amino acids and has a calculated molecular mass of 31 kDa. As a result of glycosylation, the apparent molecular mass of rhIL17RB is approximately 37 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL17RB interleukin 17 receptor B [ Homo sapiens ] |
Official Symbol : | IL17RB |
Synonyms : | IL17RB; interleukin 17 receptor B; IL17BR, interleukin 17B receptor; interleukin-17 receptor B; CRL4; EVI27; IL17RH1; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1; IL17BR; MGC5245; |
Gene ID : | 55540 |
mRNA Refseq : | NM_018725 |
Protein Refseq : | NP_061195 |
MIM : | 605458 |
UniProt ID : | Q9NRM6 |
Chromosome Location : | 3p21.1 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
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◆ Lysates | ||
IL17RB-549HCL | Recombinant Human IL17RB cell lysate | +Inquiry |
IL17RB-871HCL | Recombinant Human IL17RB cell lysate | +Inquiry |
IL17RB-1115MCL | Recombinant Mouse IL17RB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAnimal models, flow cytometry, and tissue-specific knockout strategies uncover IL17RB's involvement in inflammation and cell recruitment.
CRISPR/Cas9, siRNA, and gene editing techniques manipulate IL17RB to investigate its role in autoimmune disease pathogenesis.
Biomarker analysis, patient stratification, and clinical correlation studies investigate IL17RB's association with disease severity.
Co-receptor binding assays, protein-protein interaction studies, and functional rescue experiments reveal IL17RB's interaction partners.
In vitro wound healing assays, fibroblast activation studies, and tissue regeneration models probe IL17RB's contribution to tissue repair.
Blocking antibodies, receptor activation assays, and cytokine profiling reveal IL17RB's impact on immune responses.
Animal models, therapeutic antibody studies, and safety assessments evaluate IL17RB-targeted therapies and clinical translation challenges.
Surface plasmon resonance, ELISA, and competitive binding assays determine IL17RB's affinity for various IL17 family members.
Tumor xenograft models, immune cell infiltration assays, and gene expression analysis explore IL17RB's role in cancer biology.
Phosphorylation assays, gene expression profiling, and co-immunoprecipitation studies elucidate IL17RB-mediated signaling networks.
Customer Reviews (3)
Write a reviewHigh stability.
Good for flow cytometry.
Potent in anti-viral assays.
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