Recombinant Human ITGB3(aa 20-134) fused with His/S tag was expressed in E. coli.
Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands.
Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
Store at +4 centigradefor up to 1 month, or aliquot and store at -80 centigradefor up to 12 months. Avoid repeat freeze-thaw cycles.
Reconstitute in sterile PBS, pH 7.2-7.4.