Recombinant Human KIT (D816V) protein, GST-tagged
Cat.No. : | KIT-30H |
Product Overview : | Recombinant Human KIT (D816V) mutant fused with GST tag was expressed in E. coli. |
- Specification
- Gene Information
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Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | Phosphate-Buffered Saline (PBS), pH 7.4. No preservatives added |
Molecular Mass : | 135 kDa |
AA Sequence : | MRGARGAWDFLCVLLLLLRVQTGSS QPSVSPGEPSPPSIHPGKSDLIVRV GDEIRLLCTDPGFVKWTFEILDETN ENKQNEWITEKAEATNTGKYTCTNK HGLSNSIYVFVRDPAKLFLVDRSLY GKEDNDTLVRCPLTDPEVTNYSLKG CQGKPLPKDLRFIPDPKAGIMIKSV KRAYHRLCLHCSVDQEGKSVLSEKF ILKVRPAFKAVPVVSVSKASYLLRE GEEFTVTCTIKDVSSSVYSTWKREN SQTKL |
Purity : | >90 % as determined by SDS-PAGE analysis |
Applications : | SDS-PAGE; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at - 80 °C. Avoid repeated freeze/thaw cycles |
Gene Name : | KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog [ Homo sapiens ] |
Official Symbol : | KIT |
Synonyms : | KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; PBT, piebald trait; mast/stem cell growth factor receptor Kit; C Kit; CD117; SCFR; p145 c-kit; proto-oncogene c-Kit; piebald trait protein; soluble KIT variant 1; tyrosine-protein kinase Kit; proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; PBT; C-Kit; |
Gene ID : | 3815 |
mRNA Refseq : | NM_000222 |
Protein Refseq : | NP_000213 |
MIM : | 164920 |
UniProt ID : | P10721 |
Chromosome Location : | 4q11-q12 |
Pathway : | Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; |
Function : | ATP binding; cytokine binding; metal ion binding; nucleotide binding; protease binding; protein binding; protein homodimerization activity; protein tyrosine kinase activity; receptor activity; receptor signaling protein tyrosine kinase activity; stem cell |
Products Types
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KIT-218H | Recombinant Human KIT Protein, His-tagged | +Inquiry |
KIT-223H | Recombinant Human KIT Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
KIT-001HCL | Recombinant Human KIT cell lysate | +Inquiry |
KIT-463HCL | Recombinant Human KIT cell lysate | +Inquiry |
KIT-1324RCL | Recombinant Rat KIT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionKIT expression varies across tissues due to tissue-specific transcription factors, epigenetic modifications, and microenvironmental cues influencing its regulation.
Transcription factors like PU.1 and GATA-2, along with epigenetic modifications, regulate KIT gene expression.
KIT is crucial for germ cell survival and proliferation; mutations may lead to infertility.
KIT maintains and influences stem cell behavior, holding potential in regenerative medicine.
KIT is vital in hematopoietic stem cell development; mutations link to leukemia and mastocytosis.
Customer Reviews (3)
Write a reviewThe quality control measures are evident in the performance of this product.
Exceptional service!
Rapid delivery! Ordered and received the product within a short timeframe, allowing us to proceed with our experiments without delays.
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