Recombinant Human KIT protein, DDK/His-tagged
Cat.No. : | KIT-162H |
Product Overview : | Recombinant Human KIT(Gln26-Pro520), transcript variant 2, fused with DDK/His tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | DDK/His |
Form : | 1 x PBS, pH7.4, 10% glycerol. |
Molecular Mass : | 58 kDa |
Protein length : | Gln26-Pro520 |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | KIT KIT proto-oncogene receptor tyrosine kinase [ Homo sapiens ] |
Official Symbol : | KIT |
Synonyms : | PBT; SCFR; C-Kit; CD117 |
Gene ID : | 3815 |
mRNA Refseq : | NM_001093772 |
Protein Refseq : | NP_001087241 |
MIM : | 164920 |
UniProt ID : | P10721 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionKIT expression varies across tissues due to tissue-specific transcription factors, epigenetic modifications, and microenvironmental cues influencing its regulation.
Transcription factors like PU.1 and GATA-2, along with epigenetic modifications, regulate KIT gene expression.
KIT is crucial for germ cell survival and proliferation; mutations may lead to infertility.
KIT maintains and influences stem cell behavior, holding potential in regenerative medicine.
KIT is vital in hematopoietic stem cell development; mutations link to leukemia and mastocytosis.
Customer Reviews (3)
Write a reviewThe quality control measures are evident in the performance of this product.
Exceptional service!
Rapid delivery! Ordered and received the product within a short timeframe, allowing us to proceed with our experiments without delays.
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