| Description : |
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
84.48 kDa |
| AA Sequence : |
MIARQQCVRGGPRGFSCGSAIVGGG KRGAFSSVSMSGGAGRCSSGGFGSR SLYNLRGNKSISMSVAGSRQGACFG GAGGFGTGGFGAGGFGAGFGTGGFG GGFGGSFSGKGGPGFPVCPAGGIQE VTINQSLLTPLHVEIDPEIQKVRTE EREQIKLLNNKFASFIDKVQFLEQQ NKVLETKWNLLQQQTTTTSSKNLEP LFETYLSVLRKQLDTLGNDKGRLQS ELKTMQDSVEDFKTKYEEEINKRTA AENDFVVLKKDVDAAYLNKVELEAK VDSLNDEINFLKVLYDAELSQMQTH VSDTSVVLSMDNNRNLDLDSIIAEV RAQYEEIAQRSKAEAEALYQTKVQQ LQISVDQHGDNLKNTKSEIAELNRM IQRLRAEIENIKKQCQTLQVSVADA EQRGENALKDAHSKRVELEAALQQA KEELARMLREYQELMSVKLALDIEI ATYRKLLEGEEYRMSGECQSAVSIS VVSGSTSTGGISGGLGSGSGFGLSS GFGSGSGSGFGFGGSVSGSSSSKII STTTLNKRR |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
