Recombinant Human LAMP3 Protein, His-tagged

• Cat.No.: LAMP3-35H
• Product Overview: Recombinant human LAMP3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: LAMP3, also known as lysosome-associated membrane glycoprotein 3, is a member of the lysosome-associated membrane protein family. LAMP3 and CD68 share very similar predicted structure. It may play a role in dendritic cell function and in adaptive immunity. Overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.
• Source: Insect cell
• Species: Human
• Tag: His
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 38.8kDa (362aa)57-70KDa (SDS–PAGE under reducing conditions)
• AA Sequence: KAFPETRDYS QPTAAATVQD IKKPVQQPAK QAPHQTLAAR FMDGHITFQT AATVKIPTTT PATTKNTATT SPITYTLVTT QATPNNSHTAPPVTEVTVGP SLAPYSLPPT ITPPAHTTGT SSSTVSHTTG NTTQPSNQTT LPATLSIALH KSTTGQKPVQ PTHAPGTTAA AHNTTRTAAPASTVPGPTLA PQPSSVKTGI YQVLNGSRLC IKAEMGIQLI VQDKESVFSP RRYFNIDPNA TQASGNCGTR KSNLLLNFQG GFVNLTFTKDEESYYISEVG AYLTVSDPET IYQGIKHAVV MFQTAVGHSF KCVSEQSLQL SAHLQVKTTD VQLQAFDFED DHFGNVDECS SDYTLEHHHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >90% by SDS – PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: LAMP3 lysosomal-associated membrane protein 3 [ Homo sapiens ]
• Official Symbol: LAMP3
• Synonyms: LAMP3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; CD208; DC LAMP; DCLAMP; LAMP; TSC403; DC-lysosome-associated membrane glycoprotein; LAMP-3; DC-LAMP
• Gene ID: 27074
• mRNA Refseq: NM_014398
• Protein Refseq: NP_055213
• MIM: 605883
• UniProt ID: Q9UQV4
• Chromosome Location: 3q26.3-q27
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem