Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Recombinant Proteins > Recombinant Human LCMT1 protein, GST-tagged, Active

Recombinant Human LCMT1 protein, GST-tagged, Active

   Share
"LCMT1" Related Products.
By Species
+Expand -Collapse
By Source
+Expand -Collapse
By Tag
GST(1)
His(6)
Cat.No.:
LCMT1-187H
Product Overview:
Recombinant Human LCMT1 fused with GST tag at N-terminal was expressed in Insect cells.
Description:
Leucine carboxyl methyltransferase 1 (LCMT1) exclusively methylates the carboxyl group of leucine-309 in the catalytic subunit of protein phosphatase 2A. LCMT1 is essential for normal progression through mitosis and cell survival. Knocking-down LCMT1 leads to reduced formation of PP2A heterodimers and increased apoptosis. LCMT1 also regulates the association of PP2A and its substrate, Tau protein, with plasma membrane in neuroblastoma cells. Decreased level of PP2A methylation is found in Alzheimer disease.
Source:
Insect cells
Species:
Human
Tag :
GST
Form:
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity:
480 nmol/min/mg
Molecular Mass:
63 kDa
Purity:
>95%
Applications:
Methyltransferase Assay
Stability:
1 year at -70 centigrade from the date of shipment
Storage:
Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration:
0.1μg/μl


Online Inquiry    
Note: There will be extra charge for optional service!
Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
Please input "biomart" as verification code.
Please review Creative Biomart's privacy policy for more information.
Price does not include shipping and packaging costs.Request quote for final price.

If you have any other questions, please call
+1-631-559-9269.

online inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

facebook twitter linkedin google plus google plus

Join 10 other subscribers

24x7
CUSTOMER SERVICE
Easy access to products and services you need from our library via powerful searching tools
Copyright © 2007 - 2017 Creative Biomart. All Rights Reserved.