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Active Recombinant Human LYPD8 protein, Fc-tagged

Cat.No. : LYPD8-334H
Product Overview : Recombinant Human LYPD8(Leu20-Asn215) fused with Fc of Human IgG1 at C-terminal was expressed in CHO.
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  • Gene Information
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Description : Ly6/PLAUR domain containing 8 (LYPD8), is a GPI-linked protein with structural similarity to the urokinase-type plasminogen activator receptor (uPAR). Mature human LYPD8 contains one uPAR/Ly6 domain and a Ser/Thr/Pro-rich (STP) region that may serve as a target for protease mediated shedding as has been shown for the related C4.4A/LYPD3 molecule. Mature human LYPD8 shares 40% amino acid sequence identity with mouse and rat LYPD8.
Source : CHO
Species : Human
Tag : Fc
Predicted N Terminal : Leu20
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA. When Recombinant Human LYPD8 Fc Chimera is coated at 2 µg/mL, Recombinant Human Galectin‑3 binds with a typical ED50 = 90-540 ng/mL.
Molecular Mass : Predicted Molecular Mass: 48 kDa;SDS-PAGE: 85-100 kDa, reducing conditions.
Endotoxin : <0.10 EU per 1 μg of the protein by the LAL method.
Purity : >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage : Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 500 μg/mL in PBS.
Gene Name : LYPD8 LY6/PLAUR domain containing 8 [ Homo sapiens ]
Official Symbol : LYPD8
Synonyms : phospholipase inhibitor
Gene ID : 646627
mRNA Refseq : NM_001085474
Protein Refseq : NP_001078943
MIM : 617067
UniProt ID : Q6UX82
Chromosome Location : 1q44

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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