Recombinant Human MAP3K12 protein, Flag-tagged, Biotinylated

• Cat.No.: MAP3K12-41H
• Product Overview: Recombinant Human DLK, catalytic domain [1-520 amino acid of accession number NP_006292.3] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 63 kDa
• Purity: >88% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: MAP3K12 mitogen-activated protein kinase kinase kinase 12 [ Homo sapiens ]
• Official Symbol: MAP3K12
• Synonyms: MAP3K12; ZPK; DLK; dual leucine zipper kinase DLK; MEKK12; MUK; ZPKP1; protein kinase MUK; MAPK-upstream kinase
• Gene ID: 7786
• mRNA Refseq: NM_001193511
• Protein Refseq: NP_001180440
• MIM: 600447
• UniProt ID: Q12852
• Chromosome Location: 12q13
• Pathway: Insulin Signaling, organism-specific biosystem; MAPK Cascade, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Regulation of p38-alpha and p38-beta, organism-specific biosystem
• Function: ATP binding; MAP kinase kinase kinase activity; magnesium ion binding; nucleotide binding; protein binding; protein homodimerization activity; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity