Recombinant Human MAT2A protein, T7-tagged
Cat.No. : | MAT2A-176H |
Product Overview : | Recombinant human MAT2A (395 aa) protein fused with T7 Tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | T7 |
Form : | 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. |
AA Sequence : | MASMTGGQQMGRGEFMNGQLNGFHE AFIEEGTFLFTSESVGEGHPDKICD QISDAVLDAHLQQDPDAKVACETVA KTGMILLAGEITSRAAVDYQKVVRE AVKHIGYDDSSKGFDYKTCNVLVAL EQQSPDIAQGVHLDRNEEDIGAGDQ GLMFGYATDETEECMPLTIVLAHKL NAKLAELRRNGTLPWLRPDSKTQVT VQYMQDRGAVLPIRVHTIVISVQHD EEVCLDEMRDALKEKVIKAVVPAKY LDEDTIYHLQPSGRFVIGGPQGDAG LTGRKIIVDTYGGWGAHGGGAFSGK DYTKVDRSAAYAARWVAKSLVKGGL CRRVLVQVSYAIGVSHPLSISIFHY GTSQKSERELLEIVKKNFDLRPGVI VRDLDLKKPIYQRTAAYGHFGRDSF PWEVPKKLKY |
Purity : | >90% by SDS-PAGE. |
Storage : | Keep at -20°C for long term storage. Product is stable at 4 °C for at least 30 days. |
Gene Name : | MAT2A methionine adenosyltransferase II, alpha [ Homo sapiens ] |
Official Symbol : | MAT2A |
Synonyms : | MAT2A; MATA2; MATII; SAMS2; MAT 2; MAT-II; adoMet synthase 2; adoMet synthetase 2; methionine adenosyltransferase 2; |
Gene ID : | 4144 |
mRNA Refseq : | NM_005911 |
Protein Refseq : | NP_005902 |
MIM : | 601468 |
UniProt ID : | P31153 |
Chromosome Location : | 2p11.2 |
Pathway : | Biological oxidations, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; |
Function : | ATP binding; metal ion binding; methionine adenosyltransferase activity; nucleotide binding; transferase activity; |
Products Types
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◆ Lysates | ||
MAT2A-4454HCL | Recombinant Human MAT2A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, dysregulation of MAT2A expression has been associated with certain cancers. Understanding its role in cancer metabolism could lead to targeted therapies.
In theory, inhibiting MAT2A could alter cellular methylation patterns, making it a potential strategy for disorders characterized by abnormal methylation.
MAT2A influences cellular methylation patterns by providing SAMe, a methyl donor essential for the methylation of proteins, lipids, and nucleic acids.
SAMe, produced by MAT2A, is a precursor for neurotransmitter synthesis. Altered MAT2A function may have implications for neurological disorders like depression and schizophrenia.
MAT2A-derived SAMe is essential for DNA methylation. Aberrant DNA methylation is a hallmark of cancer, and targeting MAT2A may have implications for epigenetic cancer therapies.
Customer Reviews (3)
Write a reviewIts exceptional reliability and compatibility with various research methodologies make it an invaluable asset for scientists seeking to delve into protein-protein interactions, signaling pathways, and structural investigations.
Incorporating the ARRB2A protein into research endeavors ensures accurate and comprehensive results, bringing us closer to unraveling the complexities of cellular processes.
Its robust nature and stability make it suitable for imaging studies, providing researchers with a detailed understanding of the protein's structural characteristics.
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