"NRG4" Related Products

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Recombinant Human NRG4 Protein

Cat.No.: NRG4-452H
Product Overview: Recombinant human NRG4 (Q8WWG1) extracellular domain (Pro 2-Phe 62) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
Source: E. coli
Species: Human
Predicted N Terminal: Gly
Form: Lyophilized from sterile 50mM Tris, 50mM NaCl, pH 7.2, 5%~8% trehalose and mannitol.
Molecular Mass: The recombinant human NRG4 consists of 63 amino acids and has a calculated molecular mass of 6.7 KDa as estimated in SDS-PAGE under reducing conditions.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: >92 % as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: NRG4 neuregulin 4 [ Homo sapiens ]
Official Symbol: NRG4
Synonyms: NRG4; neuregulin 4; pro-neuregulin-4, membrane-bound isoform; HRG4; pro-NRG4; heregulin 4; DKFZp779N0541; DKFZp779N1944;
Gene ID: 145957
mRNA Refseq: NM_138573
Protein Refseq: NP_612640
MIM: 610894
UniProt ID: Q8WWG1
Chromosome Location: 15q23
Pathway: ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; GRB2 events in ERBB2 signaling, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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