Recombinant Human NTRK2 protein, Flag-tagged, Biotinylated

• Cat.No.: NTRK2-87H
• Product Overview: Recombinant Human TRKB, cytoplasmic domain [456-822(end) amino acids of accession number NP_001018074.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 45 kDa
• Purity: >90% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: NTRK2 neurotrophic tyrosine kinase, receptor, type 2 [ Homo sapiens ]
• Official Symbol: NTRK2
• Synonyms: NTRK2; TRKB; trkB tyrosine kinase; tyrosine kinase receptor B; tropomyosin-related kinase B; trk-B; GP145-TrkB
• Gene ID: 4915
• mRNA Refseq: NM_001007097
• Protein Refseq: NP_001007098
• MIM: 600456
• UniProt ID: Q16620
• Chromosome Location: 9q22.1
• Pathway: Activation of TRKA receptors, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; NGF signalling via TRKA from the plasma membrane, organism-specific biosystem; NGF-independant TRKA activation, organism-specific biosystem; Neurotrophic factor-mediated Trk receptor signaling, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem
• Function: ATP binding; brain-derived neurotrophic factor binding; brain-derived neurotrophic factor-activated receptor activity; neurotrophin-3 binding; neurotrophin-4/5 binding; nucleotide binding; protein homodimerization activity; receptor activity