Recombinant Human OGDH protein, MYC/DDK-tagged
Cat.No. : | OGDH-562H |
Product Overview : | Recombinant Human OGDH, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 111.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) [ Homo sapiens ] |
Official Symbol : | OGDH |
Synonyms : | OGDH; oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); 2-oxoglutarate dehydrogenase, mitochondrial; E1k; OGDC-E1; oxoglutarate decarboxylase; 2-oxoglutarate dehydrogenase complex component E1; oxoglutarate dehydrogenase (succinyl-transferring); OGDC; AKGDH; |
Gene ID : | 4967 |
mRNA Refseq : | NM_002541 |
Protein Refseq : | NP_002532 |
MIM : | 613022 |
UniProt ID : | Q02218 |
Chromosome Location : | 7p13-p11.2 |
Pathway : | 2-ketoglutarate dehydrogenase complex, organism-specific biosystem; 2-ketoglutarate dehydrogenase complex, conserved biosystem; Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate, organism-specific biosystem; Citrate cycle, second carbon oxidation, 2-oxoglutarate => |
Function : | oxidoreductase activity; oxoglutarate dehydrogenase (NAD+) activity; oxoglutarate dehydrogenase (succinyl-transferring) activity; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; |
Products Types
◆ Recombinant Protein | ||
OGDH-1799M | Recombinant Mouse OGDH Protein (695-1023 aa), His-SUMO-tagged | +Inquiry |
OGDH-6321M | Recombinant Mouse OGDH Protein, His (Fc)-Avi-tagged | +Inquiry |
Ogdh-4579M | Recombinant Mouse Ogdh Protein, Myc/DDK-tagged | +Inquiry |
OGDH-699H | Recombinant Human OGDH Protein (41-427 aa), His-SUMO-tagged | +Inquiry |
OGDH-119H | Recombinant Human OGDH Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Lysates | ||
OGDH-454HCL | Recombinant Human OGDH lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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