Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Recombinant Proteins > Recombinant Human PDGFD protein

Recombinant Human PDGFD protein

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Cat.No.:
PDGFD-24H
Product Overview:
Recombinant Human PDGFD was expressed in HEK293.
Description:
PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Source:
CHO
Species:
Human
Form:
Lyophilized after extensive dialysis against PBS.
Bio-activity:
ED50 < 5 μg/ml, measured in a cell proliferation assay using 3T3 cells.
Molecular Mass:
19-21 kDa, observed by reducing SDS-PAGE.
AA Sequence:
SYHDRKSKVD LDRLNDDAKR YSCTPRNYSV NIREELKLANVVFFPRCLLV QRCGGNCGCG TVNWRSCTCN SGKTVKKYHEVLQFEPGHIK RRGRAKTMAL VDIQLDHHER CDCICSSRPPR
Endotoxin:
< 0.2 EU/μg, determined by LAL method.
Purity:
> 95% as analyzed by SDS-PAGE.
Storage:
Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 centigradefrom date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 centigradeor up to 2 months at -20°C.
Reconstitution:
Reconstituted in ddH2O or PBS at 100 μg/ml.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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