Recombinant Human PFN1 protein, T7/His-tagged
Cat.No. : | PFN1-115H |
Product Overview : | Recombinant human PFN1 cDNA (2 – 140 aa) fused with T7/His/TEV cleavage site 29aa Tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | T7/His |
Form : | 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Sucrose. |
AA Sequence : | MASMTGGQQMGRGHHHHHHENLYFQ GGEFAGWNAYIDNLMADGTCQDAAI VGYKDSPSVWAAVPGKTFVNITPAE VGVLVGKDRSSFYVNGLTLGGQKCS VIRDSLLQDGEFSMDLRTKSTGGAP TFNVTVTKTDKTLVLLMGKEGVHGG LINKKCYEMASHLRRSQY |
Purity : | >90% by SDS-PAGE |
Storage : | Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days. |
Gene Name : | PFN1 profilin 1 [ Homo sapiens ] |
Official Symbol : | PFN1 |
Synonyms : | PFN1; profilin 1; profilin-1; profilin I; |
Gene ID : | 5216 |
mRNA Refseq : | NM_005022 |
Protein Refseq : | NP_005013 |
MIM : | 176610 |
UniProt ID : | P07737 |
Chromosome Location : | 17p13.2 |
Pathway : | Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem; Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem; |
Function : | Rho GTPase binding; actin binding; phosphatidylinositol-4,5-bisphosphate binding; proline-rich region binding; receptor binding; |
Products Types
◆ Recombinant Protein | ||
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PFN1-884H | Recombinant Human PFN1 Protein | +Inquiry |
PFN1-429H | Recombinant Human PFN1 Protein, His-tagged | +Inquiry |
PFN1-1655H | Recombinant Human PFN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFN1-4056R | Recombinant Rat PFN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PFN1-3269HCL | Recombinant Human PFN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (5)
Ask a questionYes, PFN1 is involved in processes such as endocytosis, cytokinesis, and cell signaling, highlighting its importance in various cellular functions.
Research on targeting PFN1 in cancer therapy is ongoing, and there are clinical trials exploring potential drugs that could inhibit PFN1 activity to impede cancer cell metastasis.
PFN1 has been found to promote cancer cell migration and invasion, suggesting its role in cancer metastasis, making it a potential target for cancer therapy.
Yes, researchers are exploring the potential of developing drugs that target PFN1 to modulate its activity, especially in the context of cancer metastasis and neurodegenerative disorders.
PFN1 regulates cell motility and migration by controlling the dynamics of actin filaments, essential components of the cell's cytoskeleton involved in cell movement.
Customer Reviews (3)
Write a reviewThe manufacturer ensures that the protein is produced with utmost purity and integrity, minimizing the risk of experimental artifacts or compromised results.
Their excellent technical support, commitment to scientific collaboration, and efficient supply chain management greatly contribute to the success and productivity of my research.
One of the key advantages of using PFN1 protein in trials is its high quality.
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