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Recombinant Human PLA2G6 protein, GST-tagged

Cat.No. : PLA2G6-185H
Product Overview : Recombinant Human PLA2G6(1 a.a. - 752 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 110.5 kDa
AA Sequence : MQFFGRLVNTFSGVTNLFSNPFRVK EVAVADYTSSDRVREEGQLILFQNT PNRTWDCVLVNPRNSQSGFRLFQLE LEADALVNFHQYSSQLLPFYESSPQ VLHTEVLQHLTDLIRNHPSWSVAHL AVELGIRECFHHSRIISCANCAENE EGCTPLHLACRKGDGEILVELVQYC HTQMDVTDYKGETVFHYAVQGDNSQ VLQLLGRNAVAGLNQVNNQGLTPLH LACQLGKQEMVRVLLLCNARCNIMG PNGYPIHSAMKFSQKGCAEMIISMD SSQIHSKDPRYGASPLHWAKNAEMA RMLLKRGCNVNSTSSAGNTALHVAV MRNRFDCAIVLLTHGANADARGEHG NTPLHLAMSKDNVEMIKALIVFGAE VDTPNDFGETPTFLASKIGRQLQDL MHISRARKPAFILGSMRDEKRTHDH LLCLDGGGVKGLIIIQLLIAIEKAS GVATKDLFDWVAGTSTGGILALAIL HSKSMAYMRGMYFRMKDEVFRGSRP YESGPLEEFLKREFGEHTKMTDVRK PKVMLTGTLSDRQPAELHLFRNYDA PETVREPRFNQNVNLRPPAQPSDQL VWRAARSSGAAPTYFRPNGRFLDGG LLANNPTLDAMTEIHEYNQDLIRKG QANKVKKLSIVVSLGTGRSPQVPVT CVDVFRPSNPWELAKTVFGAKELGK MVVDCCTDPDGRAVDRARAWCEMVG IQYFRLNPQLGTDIMLDEVSDTVLV NALWETEVYIYEHREEFQKLIQLLL SP
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot(Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) [ Homo sapiens ]
Official Symbol : PLA2G6
Synonyms : PLA2G6; phospholipase A2, group VI (cytosolic, calcium-independent); 85 kDa calcium-independent phospholipase A2; iPLA2; PARK14; PNPLA9; GVI PLA2; group VI phospholipase A2; calcium-independent phospholipase A2; patatin-like phospholipase domain containing 9; cytosolic, calcium-independent phospholipase A2; GVI; PLA2; INAD1; NBIA2A; NBIA2B; CaI-PLA2; IPLA2-VIA;
Gene ID : 8398
mRNA Refseq : NM_001004426
Protein Refseq : NP_001004426
MIM : 603604
UniProt ID : O60733
Chromosome Location : 22q13.1
Pathway : Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Eicosanoid Synthesis, organism-specific biosystem; Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem;
Function : calcium-independent phospholipase A2 activity; hydrolase activity; phospholipase A2 activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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