"PNMT" Related Products

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Recombinant Human PNMT protein, GST-tagged, Active

Cat.No.: PNMT-197H
Product Overview: Recombinant Human PNMT fused with GST tag at N-terminal was expressed in Insect cells.
Description: Phenylethanolamine N-methyltransferase (PNMT) catalyzes the biosynthesis of adrenaline though methylation of phenylethanolamine. PNMT gene is reported to be involved in various human diseases including early-onset Alzheimer disease, Parkinson's disease, and multiple sclerosis. Expression of PNMT can be stimulated by nicotine.
Source: Insect cells
Species: Human
Tag : GST
Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: 170 nmol/min/mg
Molecular Mass: 57 kDa
Purity: >95%
Applications: Methyltransferase Assay
Stability: 1 year at -70 centigrade from the date of shipment
Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: PNMT phenylethanolamine N-methyltransferase [ Homo sapiens ]
Official Symbol: PNMT
Synonyms: PNMT; phenylethanolamine N-methyltransferase; PENT; phenylethanolamine N-methylase; noradrenaline N-methyltransferase; PNMTase; MGC34570;
Gene ID: 5409
mRNA Refseq: NM_002686
Protein Refseq: NP_002677
MIM: 171190
UniProt ID: P11086
Chromosome Location: 17q
Pathway: Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Catecholamine biosynthesis, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline, organism-specific biosystem;
Function: methyltransferase activity; phenylethanolamine N-methyltransferase activity; transferase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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