Recombinant Human PPP2R1A protein, His-tagged

• Cat.No.: PPP2R1A-37H
• Product Overview: Recombinant full-length human PPP2R1A fused with His tag at N-terminal was expressed in Sf9 insect cells.

Specification

• Source: Insect cells
• Species: Human
• Tag: His
• Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
• Molecular Mass: ~66 kDa
• Purity: >75% by densitometry
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/ul
• Publication:
  CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer (2020)

Gene Information

• Gene Name: PPP2R1A protein phosphatase 2, regulatory subunit A, alpha [ Homo sapiens ]
• Official Symbol: PPP2R1A
• Synonyms: PPP2R1A; PP2A Aalpha; PR65A; PP2AAALPHA; MGC786; PP2A-Aalpha
• Gene ID: 5518
• mRNA Refseq: NM_014225
• Protein Refseq: NP_055040
• MIM: 605983
• UniProt ID: P30153
• Chromosome Location: 19q13
• Pathway: Activated TLR4 signalling, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Beta-catenin phosphorylation cascade, organism-specific biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem
• Function: antigen binding; protein binding; protein heterodimerization activity; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity