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Recombinant Human PRKAA2 protein, His/MBP-tagged

Cat.No. : PRKAA2-362H
Product Overview : Recombinant Human PRKAA2(461-536 aa) fused with His/MBP tag was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Source : E. coli
Species : Human
Tag : His/MBP
Form : Liquid in PBS
Protein length : 461-536 aa
Purity : SDS-PAGE >90%
Applications : WB Positive Control
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit [ Homo sapiens ]
Official Symbol : PRKAA2
Synonyms : PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit; PRKAA; 5-AMP-activated protein kinase catalytic subunit alpha-2; AMPK; AMPKa2; AMPK-alpha-2 chain; AMPK subunit alpha-2; 5-AMP-activated protein kinase, catalytic alpha-2 chain; AMPK2;
Gene ID : 5563
mRNA Refseq : NM_006252
Protein Refseq : NP_006243
MIM : 600497
UniProt ID : P54646

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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