"PROC" Related Products

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Recombinant Human PROC protein, His-tagged

Cat.No.: PROC-25H
Product Overview: Recombinant Human PROC(Ala43-Pro461) fused with His tag at C-terminal was expressed in CHO. The isolated protein was activated by thrombin/thrombomodulin complex and further purified.
Source: CHO
Species: Human
Tag : His
Predicted N Terminal: Ala43 (light chain) & Leu212 (heavy chain)
Form: Supplied as a 0.2 μm filtered solution in Tris, NaCl and CaCl2.
Bio-activity: Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >275 pmol/min/µg.
Molecular Mass: Predicted Molecular Mass: 19 (light chain), 29 (heavy chain) kDa;
SDS-PAGE: 22-25 kDa and 40-50 kDa, reducing conditions.
Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage: Avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening.
Gene Name: PROC protein C (inactivator of coagulation factors Va and VIIIa) [ Homo sapiens ]
Official Symbol: PROC
Synonyms: PROC; protein C (inactivator of coagulation factors Va and VIIIa); vitamin K-dependent protein C; autoprothrombin IIA; anticoagulant protein C; blood coagulation factor XIV; PC; APC; PROC1; THPH3; THPH4;
Gene ID: 5624
mRNA Refseq: NM_000312
Protein Refseq: NP_000303
MIM: 612283
UniProt ID: P04070
Chromosome Location: 2q13-q14
Pathway: Cell surface interactions at the vascular wall, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Gamma-carboxylation of protein precursors, organism-specific biosystem;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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