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Recombinant Human RBFOX2 protein, MYC/DDK-tagged

Cat.No. : RBFOX2-589H
Product Overview : Recombinant Human RBFOX2, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
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  • Gene Information
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Description : This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 40.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 [ Homo sapiens ]
Official Symbol : RBFOX2
Synonyms : RBFOX2; RNA binding protein, fox-1 homolog (C. elegans) 2; RBM9, RNA binding motif protein 9; RNA binding protein fox-1 homolog 2; FOX 2; hexaribonucleotide binding protein 2; HNRBP2; HRNBP2; fox-1 homolog B; fox-1 homologue; RNA-binding motif protein 9; hexaribonucleotide-binding protein 2; repressor of tamoxifen transcriptional activity; RTA; fxh; FOX2; RBM9; Fox-2; dJ106I20.3;
Gene ID : 23543
mRNA Refseq : NM_001031695
Protein Refseq : NP_001026865
MIM : 612149
UniProt ID : O43251
Chromosome Location : 22q12-q13
Function : RNA binding; nucleotide binding; protein binding; transcription corepressor activity; transcription factor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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