Recombinant Human ROCK1 protein, Flag-tagged, Biotinylated

• Cat.No.: ROCK1-76H
• Product Overview: Recombinant Human ROCK1, catalytic domain [1-477 amino acids of accession number NP_005397.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 59 kDa
• Purity: >90% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: ROCK1 Rho-associated, coiled-coil containing protein kinase 1 [ Homo sapiens ]
• Official Symbol: ROCK1
• Synonyms: ROCK1; p160ROCK; p160-ROCK; Rho kinase; p160 ROCK-1; renal carcinoma antigen NY-REN-35; ROCK-I; P160ROCK; PRO0435
• Gene ID: 6093
• mRNA Refseq: NM_005406
• Protein Refseq: NP_005397
• MIM: 601702
• UniProt ID: Q13464
• Chromosome Location: 18q11.2
• Pathway: Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem
• Function: ATP binding; GTP-Rho binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity