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Recombinant Human SETD2 protein, GST-tagged

Cat.No. : SETD2-260H
Product Overview : Recombinant Human SETD2(1345-1711 aa) fused with GST tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Description : SETD2 is a SET-domain containing histone methyltransferase, catalyzing the trimethylation of histone H3 at lysine 36. SETD2 is a candidate tumor suppressor protein and mutated in clear cell renal cell carcinoma.
Source : E. coli
Species : Human
Tag : GST
Form : In 50mM Tris pH 7.3, 300 mM NaCl, 4mM DTT, 1µM ZnCl2 and 25% glycerol.
Molecular Mass : 68 kDa
Applications : SETD2, Recombinant Human GST-tagged is useful for histone H3 methylation experiments, enzyme kinetics and inhibitor screening. Use of 0.5 - 2.5 µg SETD2 per reaction with nucleosomes or recombinant histone H3 as a substrate is recommended.
Storage : Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration : 1 µg/µl
Gene Name : SETD2 SET domain containing 2 [ Homo sapiens ]
Official Symbol : SETD2
Synonyms : SETD2; SET domain containing 2; histone-lysine N-methyltransferase SETD2; FLJ23184; HIF 1; HYPB; KIAA1732; KMT3A; huntingtin yeast partner B; lysine N-methyltransferase 3A; huntingtin interacting protein 1; huntingtin-interacting protein B; SET2; HIF-1; HIP-1; HBP231; HSPC069; p231HBP; FLJ16420; FLJ22472; FLJ45883; FLJ46217;
Gene ID : 29072
mRNA Refseq : NM_014159
Protein Refseq : NP_054878
MIM : 612778
UniProt ID : Q9BYW2
Chromosome Location : 3p21.31
Pathway : Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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