Active Recombinant Human SETD2 protein, GST-tagged
Cat.No. : | SETD2-199H |
Product Overview : | Recombinant Human SETD2(1425-1717 aa) fused with GST tag at N-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | As a member of the mixed lineage leukemia (MLL) family of histone methyltransferase, SETD2 specifically tri-methylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate. The main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 250 nmol/min/mg |
Molecular Mass : | 61 kDa |
Purity : | >70% |
Applications : | Methyltransferase Assay |
Stability : | 1 year at -70 centigrade from the date of shipment |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | SETD2 SET domain containing 2 [ Homo sapiens ] |
Official Symbol : | SETD2 |
Synonyms : | SETD2; SET domain containing 2; histone-lysine N-methyltransferase SETD2; FLJ23184; HIF 1; HYPB; KIAA1732; KMT3A; huntingtin yeast partner B; lysine N-methyltransferase 3A; huntingtin interacting protein 1; huntingtin-interacting protein B; SET2; HIF-1; H |
Gene ID : | 29072 |
mRNA Refseq : | NM_014159 |
Protein Refseq : | NP_054878 |
MIM : | 612778 |
UniProt ID : | Q9BYW2 |
Chromosome Location : | 3p21.31 |
Pathway : | Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; |
Function : | DNA binding; histone-lysine N-methyltransferase activity; methyltransferase activity; oxidoreductase activity; protein binding; transferase activity; transition metal ion binding; |
Products Types
◆ Recombinant Protein | ||
SETD2-460H | Recombinant Human SET Domain Containing 2, GST-tagged | +Inquiry |
SETD2-023H | Recombinant Human SETD2 Protein, His-tagged | +Inquiry |
SETD2-116H | Recombinant Human SETD2 Protein, His-tagged | +Inquiry |
SETD2-8067M | Recombinant Mouse SETD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SETD2-260H | Recombinant Human SETD2 protein, GST-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1864 | SETD2 Chemiluminescent Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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