"SETD6" Related Products

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Recombinant Human SETD6 protein, GST-tagged, Active

Cat.No.: SETD6-200H
Product Overview: Recombinant Human SETD6 fused with GST tag at N-terminal was expressed in Insect cells.
Description: SET domain-containing protein 6 (SETD6) is a mono-methyltransferase that has been shown to methylate RelA of NF-kappa-B complex and thus attenuate NF-kappa-B transcription factor activity. In addition, it monomethylates the histone H2A variant H2AZ which is required for the maintenance of embryonic stem cell self-renewal.
Source: Insect cells
Species: Human
Tag : GST
Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: 380 nmol/min/mg
Molecular Mass: 75 kDa
Purity: >80%
Applications: Methyltransferase Assay
Stability: 1 year at -70 centigrade from the date of shipment
Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: SETD6 SET domain containing 6 [ Homo sapiens ]
Official Symbol: SETD6
Synonyms: SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6;
Gene ID: 79918
mRNA Refseq: NM_001160305
Protein Refseq: NP_001153777
UniProt ID: Q8TBK2
Chromosome Location: 16q21
Function: NF-kappaB binding; methyltransferase activity; protein binding; protein-lysine N-methyltransferase activity; transferase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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