Recombinant Human SIRT2 protein, T7/His-tagged

• Cat.No.: SIRT2-174H
• Product Overview: Recombinant human SIRT2 cDNA (389aa, isoform-2) protein fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: T7/His
• Form: 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQ GGEFDFLRNLFSQTLSLGSQKERLL DELTLEGVARYMQSERCRRVICLVG AGISTSAGIPDFRSPSTGLYDNLEK YHLPYPEAIFEISYFKKHPEPFFAL AKELYPGQFKPTICHYFMRLLKDKG LLLRCYTQNIDTLERIAGLEQEDLV EAHGTFYTSHCVSASCRHEYPLSWM KEKIFSEVTPKCEDCQSLVKPDIVF FGESLPARFFSCMQSDFLKVDLLLV MGTSLQVQPFASLISKAPLSTPRLL INKEKAGQSDPFLGMIMGLGGGMDF DSKKAYRDVAWLGECDQGCLALAEL LGWKKELEDLVRREHASIDAQSGAG VPNPSTSASPKKSPPPAKDEARTTE REKPQ
• Purity: >90% by SDS-PAGE.
• Storage: Keep at -80°C for long term storage. Product is stable at 4 °C for at least 30 days.

Gene Information

• Gene Name: SIRT2 sirtuin 2 [ Homo sapiens ]
• Official Symbol: SIRT2
• Synonyms: SIRT2; sirtuin 2; NAD-dependent deacetylase sirtuin-2; sirtuin type 2; SIR2-like protein 2; SIR2; SIR2L; SIR2L2; FLJ35621; FLJ37491
• Gene ID: 22933
• mRNA Refseq: NM_030593
• Protein Refseq: NP_085096
• MIM: 604480
• UniProt ID: Q8IXJ6
• Chromosome Location: 19q13
• Pathway: Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class III, organism-specific biosystem
• Function: NOT NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity; histone acetyltransferase binding; histone deacetylase binding; hydrolase activity; metal ion binding; protein binding; protein deacetylase activity; transcription factor binding; tubulin deacetylase activity; ubiquitin binding; zinc ion binding