Recombinant Human SIRT6 protein, T7/His-tagged

• Cat.No.: SIRT6-213H
• Product Overview: Recombinant human SIRT6 cDNA (355 aa, Isoform_1) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: T7/His
• Form: 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQ GGEFSVNYAAGLSPYADKGKCGLPE IFDPPEELERKVWELARLVWQSSSV VFHTGAGISTASGIPDFRGPHGVWT MEERGLAPKFDTTFESARPTQTHMA LVQLERVGLLRFLVSQNVDGLHVRS GFPRDKLAELHGNMFVEECAKCKTQ YVRDTVVGTMGLKATGRLCTVAKAR GLRACRGELRDTILDWEDSLPDRDL ALADEASRNADLSITLGTSLQIRPS GNLPLATKRRGGRLVIVNLQPTKHD RHADLRIHGYVDEVMTRLMKHLGLE IPAWDGPRVLERALPPLPRPPTPKL EPKEESPTRINGSIPAGPKQEPCAQ HNGSEPASPKRERPTSPAPHRPPKR VKAKAVPS
• Purity: >90% by SDS-PAGE.
• Storage: Keep at -80°C for long term storage. Product is stable at 4 °C for at least 7 days.

Gene Information

• Gene Name: SIRT6 sirtuin 6 [ Homo sapiens ]
• Official Symbol: SIRT6
• Synonyms: SIRT6; sirtuin 6; NAD-dependent deacetylase sirtuin-6; sirtuin type 6; SIR2-like protein 6; sir2-related protein type 6; SIR2L6
• Gene ID: 51548
• mRNA Refseq: NM_001193285
• Protein Refseq: NP_001180214
• MIM: 606211
• UniProt ID: Q8N6T7
• Chromosome Location: 19p13.3
• Pathway: Signaling events mediated by HDAC Class I, organism-specific biosystem
• Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity; NAD-dependent histone deacetylase activity (H3-K9 specific); hydrolase activity; metal ion binding; protein binding; zinc ion binding