Recombinant Human SKP2 protein, MYC/DDK-tagged

• Cat.No.: SKP2-42H
• Product Overview: Recombinant Human SKP2, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: SKP2
• Synonyms: SKP2; S-phase kinase-associated protein 2, E3 ubiquitin protein ligase; S phase kinase associated protein 2 (p45); S-phase kinase-associated protein 2; FBL1; FBXL1; p45; p45skp2; F-box/LRR-repeat protein 1; CDK2/cyclin A-associated protein p45; S-phase kinase-associated protein 2 (p45); FLB1; MGC1366
• Gene ID: 6502
• mRNA Refseq: NM_005983
• Protein Refseq: NP_005974
• MIM: 601436
• UniProt ID: Q13309
• Chromosome Location: 5p13
• Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; C-MYC pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem
• Function: protein binding; ubiquitin-protein ligase activity