Recombinant Human SLC6A5 protein, GST-tagged
Cat.No. : | SLC6A5-118H |
Product Overview : | Recombinant Human SLC6A5(294 a.a. - 393 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 36.74 kDa |
AA Sequence : | TLFYLFASFVSVLPWGSCNNPWNTP ECKDKTKLLLDSCVISDHPKIQIKN STFCMTAYPNVTMVNFTSQANKTFV SGSEEYFKYFVLKISAGIEYPGEIR |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | SLC6A5 solute carrier family 6 (neurotransmitter transporter, glycine), member 5 [ Homo sapiens ] |
Official Symbol : | SLC6A5 |
Synonyms : | SLC6A5; solute carrier family 6 (neurotransmitter transporter, glycine), member 5; NET1; sodium- and chloride-dependent glycine transporter 2; GLYT2; GLYT-2; |
Gene ID : | 9152 |
mRNA Refseq : | NM_004211 |
Protein Refseq : | NP_004202 |
MIM : | 604159 |
UniProt ID : | Q9Y345 |
Chromosome Location : | 11p15.1 |
Pathway : | Na+/Cl- dependent neurotransmitter transporters, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem; |
Function : | glycine:sodium symporter activity; neurotransmitter:sodium symporter activity; symporter activity; |
Products Types
◆ Recombinant Protein | ||
SLC6A5-4083H | Recombinant Human SLC6A5 Protein, His (Fc)-Avi-tagged | +Inquiry |
SLC6A5-1207H | Recombinant Human SLC6A5 Protein (D2-C797), 8×His-Strep, Flag tagged | +Inquiry |
SLC6A5-2951H | Recombinant Human SLC6A5 protein, His-tagged | +Inquiry |
SLC6A5-1947Z | Recombinant Zebrafish SLC6A5 | +Inquiry |
SLC6A5-683H | Recombinant Human SLC6A5 | +Inquiry |
◆ Lysates | ||
SLC6A5-1704HCL | Recombinant Human SLC6A5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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