Recombinant Human TIMP2 Protein, His-tagged
Cat.No. : | TIMP2-37H |
Product Overview : | Recombinant human TIMP2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | TIMP2, also known as metalloproteinase inhibitor 2, belongs to the tissue inhibitors of metalloproteinases family. The TIMP family inhibit most MMPs by forming non-covalent binary complex. TIMP2 plays a unique role among TIMP family members owing to its functions to regulate cellular responses to growth factors. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 22.5kDa (200aa)18-28KDa (SDS–PAGE under reducing conditions.) |
AA Sequence : | CSCSPVHPQQ AFCNADVVIR AKAVSEKEVD SGNDIYGNPI KRIQYEIKQI KMFKGPEKDI EFIYTAPSSA VCGVSLDVGG KKEYLIAGKAEGDGKMHITL CDFIVPWDTL STTQKKSLNH RYQMGCECKI TRCPMIPCYI SSPDECLWMD WVTEKNINGH QAKFFACIKR SDGSCAWYRGAAPPKQEFLD IEDPHHHHHH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | >95% by SDS – PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Absorbance at 280nm) |
Gene Name : | TIMP2 TIMP metallopeptidase inhibitor 2 [ Homo sapiens ] |
Official Symbol : | TIMP2 |
Synonyms : | TIMP2; TIMP metallopeptidase inhibitor 2; tissue inhibitor of metalloproteinase 2; metalloproteinase inhibitor 2; CSC 21K; TIMP-2; tissue inhibitor of metalloproteinases 2; CSC-21K; |
Gene ID : | 7077 |
mRNA Refseq : | NM_003255 |
Protein Refseq : | NP_003246 |
MIM : | 188825 |
UniProt ID : | P16035 |
Chromosome Location : | 17q25 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem; |
Function : | enzyme activator activity; enzyme inhibitor activity; integrin binding; metal ion binding; metalloendopeptidase inhibitor activity; |
Products Types
◆ Recombinant Protein | ||
Timp2-6437M | Recombinant Mouse Timp2 Protein, Myc/DDK-tagged | +Inquiry |
TIMP2-5734R | Recombinant Rat TIMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Timp2-10621M | Recombinant Mouse Timp2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TIMP2-3835H | Active Recombinant Human TIMP2 protein(Cys27-Pro220) | +Inquiry |
TIMP2-1027H | Recombinant Human TIMP2 Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
TIMP2-8460H | Native Human TIMP2 | +Inquiry |
◆ Lysates | ||
TIMP2-2061HCL | Recombinant Human TIMP2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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