Recombinant Human TSHB protein, MYC/DDK-tagged

• Cat.No.: TSHB-185H
• Product Overview: Recombinant Human TSHB fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 13.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TSHB thyroid stimulating hormone, beta [ Homo sapiens ]
• Official Symbol: TSHB
• Synonyms: TSHB; thyroid stimulating hormone, beta; thyrotropin subunit beta; thyrotropin beta chain; thyrotropin beta subunit; thyroid-stimulating hormone subunit beta; TSH-B; TSH-BETA
• Gene ID: 7252
• mRNA Refseq: NM_000549
• Protein Refseq: NP_000540
• MIM: 188540
• UniProt ID: P01222