Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human WNT3A protein, GST-tagged

Cat.No. : WNT3A-4930H
Product Overview : Recombinant Human WNT3A(1 a.a. - 385 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
  • Specification
  • Gene Information
  • Related Products
Description : The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 69.3 kDa
AA Sequence : MAPLGYFLLLCSLKQALGSYPIWWS LAVGPQYSSLGSQPILCASIPGLVP KQLRFCRNYVEIMPSVAEGIKIGIQ ECQHQFRGRRWNCTTVHDSLAIFGP VLDKATRESAFVHAIASAGVAFAVT RSCAEGTAAICGCSSRHQGSPGKGW KWGGCSEDIEFGGMVSREFADAREN RPDARSAMNRHNNEAGRQAIASHMH LKCKCHGLSGSCEVKTCWWSQPDFR AIGDFLKDKYDSASEMVVEKHRESR GWVETLRPRYTYFKVPTERDLVYYE ASPNFCEPNPETGSFGTRDRTCNVS SHGIDGCDLLCCGRGHNARAERRRE KCRCVFHWCCYVSCQECTRVYDVHT CKNPGSRAGNSAHQPPHPQPPVRFH PPLRRAGKVP
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : WNT3A wingless-type MMTV integration site family, member 3A [ Homo sapiens ]
Official Symbol : WNT3A
Synonyms : WNT3A; wingless-type MMTV integration site family, member 3A; protein Wnt-3a; MGC119418; MGC119419; MGC119420;
Gene ID : 89780
mRNA Refseq : NM_033131
Protein Refseq : NP_149122
MIM : 606359
UniProt ID : P56704
Chromosome Location : 1q42
Pathway : Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem;
Function : extracellular matrix structural constituent; frizzled-2 binding; protein binding; protein domain specific binding; receptor agonist activity; transcription coactivator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Does CDH16 protein interact with WNT3A protein? 12/14/2019

No interaction between CDH16 protein and WNT3A protein has been found.

Which role of WNT3A protein in embryonic development? 09/15/2019

The WNT3A protein plays an important role in embryonic development. It is involved in the formation of multiple embryonic organs, directed cell migration, and the establishment of tissue polarity.

Have regulators of WNT3A protein been identified? 08/24/2019

Yes, multiple factors have been found in the WNT signaling pathway that regulate the expression and function of WNT3A protein, including Axin, APC, etc.

Where is the WNT3A protein in the Wnt signaling pathway? 05/18/2019

The WNT3A protein is in the starting position in the Wnt signaling pathway, and it is able to bind to the Wnt receptor and initiate the signaling cascade.

What is the relationship between WNT3A protein and cancer stem cells? 05/04/2019

WNT3A protein is closely related to cancer stem cells. It may be involved in the self-renewal and differentiation regulation of cancer stem cells, which is of great significance for tumor development and treatment.

How about the current clinical research progress on WNT3A protein? 03/28/2019

Clinical research on WNT3A protein is still ongoing. Studies have shown the important role of WNT3A protein in tumors, neurological diseases, bone metabolism diseases, etc., and future research will further explore its application potential in disease diagnosis, treatment and prognosis assessment.

Customer Reviews (3)

Write a review
Reviews
07/15/2022

    This protein is highly expressed and can efficiently synthesize a large number of target proteins in host cells.

    06/03/2022

      This protein has therapeutic effects on specific disease models and is a promising candidate for new drugs.

      11/20/2019

        The laboratory personnel feedback that the protein is easy to operate, can meet the experimental needs, and has a good cost performance.

        Ask a Question for All WNT3A Products

        Required fields are marked with *

        My Review for All WNT3A Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends