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Recombinant Human XCL1 Protein, His-tagged

Cat.No. : XCL1-241H
Product Overview : Recombinant human XCL1 (P47992) (Met 1-Gly 114) was expressed, fused with a polyhistidine tag at the C-terminus.
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Source : Baculovirus-Insect Cells
Species : Human
Tag : His
Predicted N Terminal : Val 22
Form : Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 5%~8% trehalose and mannitol.
Molecular Mass : The recombinant human XCL1 consists of 103 amino acids and predicts a molecular mass of 11.6 kDa. The apparent molecular mass of rhXCL1 is approximately 15-20 kDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >85 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : XCL1 chemokine (C motif) ligand 1 [ Homo sapiens ]
Official Symbol : XCL1
Synonyms : XCL1; chemokine (C motif) ligand 1; LTN, SCYC1, small inducible cytokine subfamily C, member 1 (lymphotactin); lymphotactin; ATAC; LPTN; SCM 1; SCM 1a; SCM-1-alpha; lymphotaxin; cytokine SCM-1; c motif chemokine 1; XC chemokine ligand 1; single cysteine motif 1a; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin); LTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a;
Gene ID : 6375
mRNA Refseq : NM_002995
Protein Refseq : NP_002986
MIM : 600250
UniProt ID : P47992
Chromosome Location : 1q24.2
Pathway : Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (q) signalling events, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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What is known about the regulation of XCL1 expression, and how do various stimuli modulate its secretion in the context of inflammatory responses and immune activation? 01/22/2022

XCL1 expression is regulated by various stimuli, including inflammatory signals. Understanding how these stimuli modulate XCL1 secretion provides insights into its dynamic role in immune activation.

How does XCL1 influence the differentiation and function of dendritic cells, and are there implications for the modulation of adaptive immune responses? 03/01/2021

XCL1 influences the differentiation and function of dendritic cells, affecting the priming and activation of T cells. Understanding these processes has implications for modulating adaptive immune responses in various contexts.

How does XCL1 contribute to the formation of immune synapses between dendritic cells and T cells, and what molecular events underlie this process? 07/14/2020

XCL1 is involved in the formation of immune synapses between dendritic cells and T cells. Molecular events include the coordinated expression of adhesion molecules and the release of other signaling molecules.

Can you discuss the molecular mechanisms through which XCL1 interacts with its receptor XCR1, and how this interaction influences immune cell function? 02/26/2019

XCL1 binds to its receptor XCR1, initiating intracellular signaling cascades. This interaction influences immune cell function by directing the migration and activation of specific immune cell subsets.

In infectious diseases, particularly viral infections, what evidence supports the involvement of XCL1 in the host immune response, and how might it influence the outcome of infections? 09/20/2018

XCL1 is implicated in the host immune response to viral infections. Its role in recruiting and activating immune cells may influence the outcome of infections, impacting viral clearance and immune memory.

Customer Reviews (3)

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Reviews
03/30/2022

    Consistent high quality, responsive customer service, and seamless delivery

    07/10/2019

      Commendable product quality, professional customer service, and punctual delivery.

      09/05/2018

        Outstanding product quality, swift delivery, and helpful customer service. Highly recommend!

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