Recombinant Human XRCC4 protein, MYC/DDK-tagged
Cat.No. : | XRCC4-1004H |
Product Overview : | Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 1 was expressed in human HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 37.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | XRCC4 X-ray repair cross complementing 4 [ Homo sapiens (human) ] |
Official Symbol : | XRCC4 |
Synonyms : | SSMED; SSMED |
Gene ID : | 7518 |
mRNA Refseq : | NM_003401 |
Protein Refseq : | NP_003392 |
MIM : | 194363 |
UniProt ID : | Q13426 |
Products Types
◆ Recombinant Protein | ||
Xrcc4-364M | Recombinant Mouse Xrcc4 Protein, MYC/DDK-tagged | +Inquiry |
XRCC4-078H | Recombinant Human XRCC4 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
XRCC4-2370H | Recombinant Human XRCC4 Protein, His (Fc)-Avi-tagged | +Inquiry |
XRCC4-2852H | Recombinant Human XRCC4 protein(11-330 aa), C-His-tagged | +Inquiry |
XRCC4-833C | Recombinant Cynomolgus Monkey XRCC4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
XRCC4-255HCL | Recombinant Human XRCC4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionResistance mechanisms and potential side effects of XRCC4-targeted therapies pose challenges in cancer treatment.
Understanding XRCC4 function may lead to the development of targeted therapies to enhance cancer treatment efficacy.
XRCC4 is a potential target for the development of novel cancer therapies aimed at disrupting DNA repair mechanisms.
XRCC4 levels or mutations may have potential as biomarkers for certain cancers and their response to treatment.
Certain genetic variations in XRCC4 have been associated with an increased risk of developing certain types of cancer.
Customer Reviews (3)
Write a reviewTheir team of experts is readily available to address any issues that may arise, providing solutions to problems and guiding me through the experimental process.
Its seamless integration makes it possible to explore different research avenues, expanding the scope and impact of my investigations.
With the manufacturer's excellent technical support and its wide range of applications, the XRCC4 protein has become an indispensable tool, aiding in my research endeavors and driving meaningful scientific discoveries.
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