Recombinant Mouse AGTRAP Protein
Cat.No. : | AGTRAP-1433M |
Product Overview : | Recombinant Mouse AGTRAP full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Agtrap angiotensin II, type I receptor-associated protein [ Mus musculus ] |
Official Symbol : | AGTRAP |
Gene ID : | 11610 |
mRNA Refseq : | NM_009642.4 |
Protein Refseq : | NP_033772.2 |
MIM : | |
UniProt ID : | Q9WVK0 |
Products Types
◆ Recombinant Protein | ||
AGTRAP-399M | Recombinant Mouse AGTRAP Protein, His (Fc)-Avi-tagged | +Inquiry |
AGTRAP-102R | Recombinant Rhesus Macaque AGTRAP Protein, His (Fc)-Avi-tagged | +Inquiry |
AGTRAP-224R | Recombinant Rat AGTRAP Protein, His (Fc)-Avi-tagged | +Inquiry |
Agtrap-98M | Recombinant Mouse Agtrap Protein, His&GST-tagged | +Inquiry |
AGTRAP-17H | Recombinant Human AGTRAP protein, GST-tagged | +Inquiry |
◆ Lysates | ||
AGTRAP-8968HCL | Recombinant Human AGTRAP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionYes, dysregulation of AGTRAP expression or function has been implicated in various cardiovascular conditions, including hypertension, cardiac hypertrophy, and heart failure.
Yes, AGTRAP can regulate AGTR1 expression by influencing its trafficking and degradation, thus impacting the overall abundance of AGTR1 receptors.
AGTRAP can modulate AGTR1 signaling by affecting the receptor's coupling to downstream signaling pathways, including G proteins and β-arrestins.
AGTRAP is widely expressed in various tissues, including the heart, kidney, liver, and brain.
AGTRAP acts as a negative regulator of AGTR1, thereby modulating the effects of angiotensin II on blood pressure control and vascular function.
AGTRAP is primarily localized in the endoplasmic reticulum (ER) and Golgi apparatus, where it interacts with AGTR1 during receptor maturation and trafficking.
AGTRAP physically associates with AGTR1 and modulates its activity by influencing receptor trafficking, signaling, and desensitization.
While the precise involvement of AGTRAP in specific diseases is still being elucidated, dysregulation of AGTRAP has been associated with cardiovascular diseases, hypertension, and altered response to angiotensin II.
AGTRAP has been reported to interact with several proteins involved in receptor trafficking, including G protein-coupled receptor-associated sorting proteins (GASP), which influence AGTR1 cell surface expression.
Techniques such as immunoprecipitation, co-immunoprecipitation, fluorescence microscopy, and genetic manipulation in cellular and animal models are employed to investigate AGTRAP's role and molecular mechanisms.
Customer Reviews (5)
Write a reviewIt was delivered quickly, and the product was of exceptional quality, meeting all my research needs.
Outstanding products. Impressive results!
The protein I purchased was a game-changer for my experiments. Its high activity and purity significantly improved the reliability of my findings
Reliable and high-quality protein. Recommended!
I've been using proteins for years, and this one ranks among the best.
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