Recombinant Mouse ALPL Protein
Cat.No. : | ALPL-1575M |
Product Overview : | Recombinant Mouse ALPL full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Alpl alkaline phosphatase, liver/bone/kidney [ Mus musculus ] |
Official Symbol : | ALPL |
Gene ID : | 11647 |
mRNA Refseq : | NM_007431.2 |
Protein Refseq : | NP_031457.2 |
MIM : | |
UniProt ID : | P09242 |
Products Types
◆ Recombinant Protein | ||
Alpl-564M | Recombinant Mouse Alpl Protein, MYC/DDK-tagged | +Inquiry |
ALPL-2458H | Recombinant Human ALPL Protein, His (Fc)-Avi-tagged | +Inquiry |
ALPL-2155R | Recombinant Rat ALPL Protein (18-501 aa), His-SUMO-tagged | +Inquiry |
ALPL-123C | Recombinant Cattle ALPL Protein, His-tagged | +Inquiry |
ALPL-327H | Active Recombinant Human ALPL Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
ALPL-25H | Active Native Human ALPL Protein | +Inquiry |
ALPL-66C | Active Native Calf Alkaline Phosphatase | +Inquiry |
ALPL-8004H | Native Human Liver Alkaline Phosphatase | +Inquiry |
◆ Lysates | ||
ALPL-3092HCL | Recombinant Human ALPL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (10)
Ask a questionALPL exhibits tissue-specific expression, with high levels in mineralizing tissues such as bones and teeth, but lower levels in other organs.
ALPL activity and expression undergo dynamic changes during development and aging, reflecting the physiological demands for mineralization.
ALPL activity can be modulated by factors such as pyrophosphate, calcium, and inhibitors like levamisole, which impact mineralization outcomes.
ALPL plays a critical role in mineralization processes by generating inorganic phosphate, an essential component of hydroxyapatite crystals in bones and teeth.
ALPL can serve as a diagnostic marker for hypophosphatasia and related mineralization disorders, and therapeutic strategies targeting ALPL are being explored.
ALPL deficiency or dysregulation is associated with hypophosphatasia, a genetic disorder characterized by impaired mineralization and skeletal abnormalities.
Genetic variations or mutations in the ALPL gene can lead to altered enzyme activity, affecting mineralization and contributing to disease phenotypes.
Manipulating ALPL activity and function holds promise for promoting bone regeneration and dental tissue engineering, enhancing mineralization processes and tissue formation.
ALPL regulates molecular interactions and signaling pathways, including Wnt/尾-catenin, BMP, and FGF signaling, to orchestrate mineralization processes.
ALPL gene expression is regulated by transcription factors, epigenetic modifications, and signaling pathways involved in skeletal development and mineralization.
Customer Reviews (3)
Write a reviewEfficient target protein purification.
Reliable antibody for Western blotting.
Robust enzyme activity measurement.
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