Recombinant Mouse Adamts7 protein, His-tagged
Cat.No. : | Adamts7-512M |
Product Overview : | Recombinant Mouse Adamts7(Lys226~Pro437) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
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Description : | This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent enzyme that degrades cartilage oligomeric matrix protein. The deficiency of the encoded protein decreases atherosclerosis in genetically hyperlipidemic mice and in response to vascular injury. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Molecular Mass : | 25.2 kDa |
AA Sequence : | KWVET LVVADSKMVE YHGQPQVESY VLTIMNMVAG LFHDPSIGNP IHISIVRLII LEDEEKDLKI THHAEETLKN FCRWQKNINI KGDDHPQHHD TAILLTRKDL CASMNQPCET LGLSHVSGLC HPQLSCSVSE DTGMPLAFTV AHELGHSFGI QHDGTGNDCE SIGKRPFIMS PQLLYDRGIP LTWSRCSREY ITRFLDRGWG LCLDDRP |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 90% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Adamts7 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 [ Mus musculus ] |
Official Symbol : | Adamts7 |
Synonyms : | ADAMTS7; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7; A disintegrin and metalloproteinase with thrombospondin motifs 7; COMPase; ADAMTS-7; ADAM-TS 7; metalloprotease; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; ADAM-TS7; ADAMTS7B; |
Gene ID : | 108153 |
mRNA Refseq : | NM_001003911 |
Protein Refseq : | NP_001003911 |
Chromosome Location : | 9; 9 E3.1 |
Function : | hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
ADAMTS7-163R | Recombinant Rat ADAMTS7 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAMTS7-1729H | Recombinant Human ADAMTS7 Protein (242-593 aa), His-tagged | +Inquiry |
ADAMTS7-1156H | Recombinant Human ADAMTS7 Protein (242-593 aa), His-SUMO-tagged | +Inquiry |
ADAMTS7-18H | Recombinant Human ADAMTS7 protein, His-tagged | +Inquiry |
ADAMTS7-3008M | Recombinant Mouse ADAMTS7, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionADAMTS7 is also currently used in the study of diseases such as hepatocellular carcinoma and oral cancer.
ADAMTS7 can cleave TSP1.
ADAMTS7 is involved in mediating endothelial proliferation and vascular smooth muscle cell migration after arterial balloon injury. It also promotes degradation of thrombin-sensitive protein-1, inhibits reendothelialization of injured arteries, and promotes vascular remodeling.
ADAMTS7 has the highest homology with ADAMTS12.
ADAMTS7 is strongly associated with atherosclerosis, acute myocardial infarction and ischemia/reperfusion injury.
Customer Reviews (3)
Write a reviewCustomer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.
The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.
The after-sales service of the product is guaranteed, which has helped me solve many problems in the experiment.
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